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一、基本信息
田慧彬,女,博士,副教授,硕士研究生导师
研究方向:羊基因编辑与脂质代谢调控
Email:tianhb@lzu.edu.cn
通讯地址:甘肃省兰州市城关区嘉峪关西路768号,邮编:730020
二、教育与工作经历
2023.03-至今,hjc888黄金城官网入口,hjc888黄金城官网入口,副教授
2019.06-2023.02,西北农林科技大学,兽医学,博士后
2014.09-2019.06,西北农林科技大学,动物遗传育种与繁殖,博士
2010.09-2014.06,西北农林科技大学,生物科学创新实验班,学士
三、科研项目
1. hjc888黄金城官网入口人才引进科研启动费,2023-2028,主持
2. 国家自然科学基金青年项目,奶山羊C/EBPα基因调控乳腺脂肪酸代谢的分子机制研究,2021-2023,主持
3. 中国博士后科学基金面上项目,奶山羊FADS2基因对乳腺脂肪酸代谢的调控机理研究,2020-2022,主持
四、发表论文
1. Tian Huibin, Luo Jun*, Guo Peng, Li Chun, Zhang Xueying. C/EBPα promotes triacylglycerol synthesis via regulating PPARG promoter activity in goat mammary epithelial cells. Journal of Animal Science. 2023, 101, skac412.
2. Tian Huibin, Niu Huimin, Luo Jun*, Yao Weiwei, Chen Xiaoying, Wu Jiao, Geng Yanan, Gao Wenchang, Lei Anmin, Gao Zhimin, Tian Xiue, Zhao Xiaoe, Shi Huaiping, Li Cong, Hua Jinlian*. Knockout of stearoyl-CoA desaturase 1 decreased milk fat and unsaturated fatty acid contents of the goat model generated by CRISPR/Cas9. Journal of Agricultural and Food Chemistry. 2022, 70(13), 4030?4043.
3. Tian Huibin, Niu Huimin, Luo Jun*, Yao Weiwei, Gao Wenchang, Wen Yang, Cheng Min, Lei Anmin, Hua Jinlian*. Effects of CRISPR/Cas9-mediated stearoyl-Coenzyme A desaturase 1 knockout on mouse embryo development and lipid synthesis. PeerJ. 2022, 10:e13945.
4. Tian Huibin, Luo Jun*, Shi Hengbo, Chen Xiaoying, Wu Jiao, Liang Yusheng, Li Cong, Loor Juan J. Role of peroxisome proliferator-activated receptor-α on the synthesis of monounsaturated fatty acids in goat mammary epithelial cells. Journal of Animal Science. 2020, 98(3), skaa062.
5. Huang Lian#, Tian Huibin#, Luo Jun*, Song Ning, Wu Jiao. CRISPR/Cas9 based knockout of miR-145 affects intracellular fatty acid metabolism by targeting INSIG1 in goat mammary epithelial cells. Journal of Agricultural and Food Chemistry. 2020, 68(18), 5138-5146.
6. Tian Huibin, Luo Jun*, Zhang Zhifei, Wu Jiao, Zhang Tianying, Busato Sebastiano, Huang Lian, Song Ning, Bionaz Massimo*. CRISPR/Cas9-mediated stearoyl-CoA desaturase 1 (SCD1) deficiency affects fatty acid metabolism in goat mammary epithelial cells. Journal of Agricultural and Food Chemistry. 2018, 66(38), 10041-10052.